Patient Information
CYMBALTA (Duloxetine)
General Guidelines:
Cymbalta is one of the few drugs to treat neuropathic pain that is unlikely to lead to overweight
Adequate trial at a given dose might take 4-6 weeks
Pain relief usually occurs before antidepressants effects, i.e., less than one week
Minimize side effects:
- Start at lower dose, e.g., 30 mg / day Cymbalta and then increase the dose slowly. Cymbalta has been used up to 120 mg / day to treat chronic pain.
- Nausea is the most common side effect and is likely to disappear in 7-10 days
- Consider combining treatment with Cymbalta with another class of drug used to treat neuropathic pain (e.g. Lyrica)
Side effects of CYMBALTA:
- Nausea
- Dry mouth
- Constipation
- Loss of appetite
- Tiredness
- Drowsiness
- Dizziness
- Increased sweating
- Blurred vision
- Yawning
Patient exclusion criteria:
- Epileptic Seizure
- Closed Angle Glaucoma
- High Blood Pressure
- Blood Pressure Drop Upon Standing
- Hardening of the Liver caused by Alcohol
- Chronic Inflammation of the Liver
- Hardening of the Liver
- Liver Problems
- Serious Kidney Problems
- Manic-Depression,
- Having Thoughts of Suicide
- Habit of Drinking Too Much Alcohol
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 Medication
The topics presented on this site are for informational purposes only.
Any decision you make regarding your health care options should be made after consulting a qualified physician provider.
The RSD / CRPS Treatment Center and Research Institute is a licensed Ambulatory Surgical Center that is approved by the Florida Board of Medicine for Level II surgery.
The facility is regulated pursuant to the rules of the Board of Medicine as set forth in Rule Chapter 64B8, F.A.C.
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